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Our StoryOur Story
In 1995, a group of American biochemical experts who were the earliest engaged in peptide research and peptide synthesis designed and manufactured a fully automatic peptide synthesizer based on the needs of large-scale synthesis of difficult and ultra-long peptides. The application of the principle of no dead-angle stirring and reagent recycling in peptide synthesis not only greatly improves the solid-phase synthesis efficiency, but also reduces the cost of use, making the operation more convenient and safer – this is the prototype of the PSI peptide synthesizer.
From 1988 to 2000, John Ye served as the chief scientist of United Biomedical, Inc., USA, and was responsible for the R&D of peptide diagnostic reagents, peptide vaccines and the production of GMP peptide vaccines.
During the process of producing peptide raw materials of peptide foot-and-mouth disease vaccine, Dr. Ye found that the traditional SPPS adopts the mixing mode that “reactor fixed, and the collision between solid-phase resin and reactant is driven by agitator”. In the manner, the resin will be easily deformed and damaged, and largely reduce the coupling rate; moreover, the fragments of broken resin will clog the sieve plate, which will affect the liquid discharge speed. In order to avoid resin breakage, in 1995, Dr. Ye successfully tested the mixing mode without stirring paddle which “reactor turns up-and-down to drive the resin to collide violently with the reactant”. This laid a foundation of the production of super long peptide of foot-and-mouth disease vaccine.
In order to ensure the security of electronic data of the operation log, as well as meet the US FDA standards, in 2000, Dr. Ye successfully developed the electronic record and electronic signature which complies with US FDA 21 CFR Part 11; aimed to reduce of cost of waste liquid treatment, in 2001, Dr. Ye invented the solvent recycling system, and directly saved 40% washing solvent; to guarantee the equipment material's chemical stability, in 2001, Dr. Ye developed a production scale automatic peptide synthesizer which is fully made of 316L stainless steel.
In 2002, experts initiated the establishment of American Peptide Technology Co., Ltd. (PSI) in New York, USA, dedicated to providing world-class peptide synthesizers to experts engaged in peptide research and peptide production, hoping to promote global peptide research and its development. Achieve faster development of industrialization.
Our TeamOur Team
In 2000, the team with Mr. John Ye as the core, designed and manufactured a more professional production-oriented peptide synthesizer with the international advanced technology to solve the large-scale production of a difficult ultra-long peptide, holding the careful thinking, advanced concept and professional vision of scientists.
Peptide Scientific Inc. (PSI) is one of the leading companies in the world for peptide research and instrumentation.
PSI manufactures the most advanced peptide synthesizers on the market for the GMP pharmaceutical peptide production, as well as for the peptide Research and Development.
Our instruments are designed by experienced peptide chemists who are professional in peptide synthesis field. All of our instruments have the unique system to ensure the homogeneous mixing during the reaction—the key to produce peptides in high purity. PSI earned reputations from our customers all over the world for the efficient, robust, versatile, flexible, reliable and affordable peptide synthesizers.
During these two decades, our team has grown and attracted talented people from different fields and cultures, who bring with them a wealth of experience and unique perspectives that allow us to continually refine our instruments.
Since our foundation, we have always insisted on our own requirements, pursuing excellence and perfection. We are constantly learning and improving, and always maintain a keen insight into the latest technology and trends in the industry. We have a wealth of experience and deep knowledge in our professional field, which enables us to stand out in the market competition and win the trust and respect of our customers and partners.
Currently PSI offers 9 different models of products to the universities, research institutes, medical centers, peptide core facilities, biotech companies and pharmaceutical companies. These instruments cover all peptide synthesis requirements with different synthesis scales, different chemistry.
Our future vision is to become a global leader and innovation promoter in the field of peptide synthesis, to provide the best quality products and services to our customers, to jointly promote the development and progress of the peptide field, and to make our contribution to the development of human health and life sciences.