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China Suppliers Factory: PepAxis™ - Industrial Grade Peptide Synthesizer with Advanced Features and Monitoring
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China Suppliers Factory: PepAxis™ - Industrial Grade Peptide Synthesizer with Advanced Features and Monitoring

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6861.png  Introducing our large-volume dual-jacket temperature-controlled reactors featuring viewports, ideal for efficient chemical processing. As a leading Factory in China, we ensure high-quality manufacturing standards for optimal performance.

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6862.png  Our reactors are equipped with real-time monitoring systems and alarms for pressure, solvent temperature, and stirring speed, making them a reliable choice for suppliers seeking advanced technology solutions.

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286  Experience precise quantitative solvent transfer with our metering pumps, designed to enhance efficiency in your operations. Partner with us, a trusted Factory in China, for comprehensive support and top-tier chemical processing equipment.

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    Product Profile

    PepAxis™-Sirius (formerly 686) is a high-reliability industrial-grade customized peptide synthesis system designed for large-scale industrial production. The system adopts a modular customized design, with reactor volumes ranging from 30 to 2000 L and synthesis scales of 0.3 mol and above, meeting the requirements of continuous and large-batch production.

    The system is equipped with a double-jacketed temperature-controlled reactor, an amino acid activation tank, and a piperidine buffer tank, all featuring sight-glass designs for real-time monitoring of pressure, temperature, and stirring status, ensuring full-process controllability and traceability. It supports multi-solvent position management and precise quantitative transfer via metering pumps.

    Combined with mechanical agitation and a wide temperature control range (–20 to 50 °C), the system effectively ensures process stability and reproducibility.

    The system is certified for explosion protection and equipped with automatic alarm mechanisms, making it suitable for industrial-scale peptide drug production, process scale-up, and customized synthesis applications, providing customers with a safe, efficient, and scalable synthesis solution.

    Basic Parameters

    Model Channels Reactor (L) Amino Acid Tank Deprotection Tank Synthesis Scale (mol)
    PepAxis-Sirius 1 30~2000 1 1 ≥ 0.3

    Technical Parameters

    Temperature Control Medium
    Water / Ethylene Glycol
    Solvent Stations
    ≤ 9
    Reaction Vessel Material
    304 Stainless Steel Lined with 316L Stainless Steel
    Stirring Mode
    Paddle Stirring
    Amino Acid Activation Tank
    304 Stainless Steel with 316L Stainless Steel Lining
    Deprotection Buffer Tank
    304 Stainless Steel with 316L Stainless Steel Lining
    Explosion-Proof Rating
    220 / 380V

    Frequently Asked Questions

    Q What reactor volume range does the PepAxis™-Sirius system support?
    The PepAxis™-Sirius system supports reactor volumes ranging from 30 to 2000 L, making it suitable for both pilot-scale and full industrial-scale peptide production.
    Q What is the minimum synthesis scale for this system?
    The system supports synthesis scales of 0.3 mol and above, accommodating large-batch continuous production requirements.
    Q What temperature control range does the PepAxis™-Sirius offer?
    The system provides a wide temperature control range of –20 to 50 °C, using water or ethylene glycol as the temperature control medium, ensuring process stability across diverse synthesis conditions.
    Q What materials are used for the reactor and tanks?
    The reaction vessel, amino acid activation tank, and deprotection buffer tank are all constructed from 304 stainless steel lined with 316L stainless steel, ensuring excellent chemical resistance and durability in industrial environments.
    Q Is the PepAxis™-Sirius system safe for use in hazardous production environments?
    Yes. The system is certified for explosion protection (220/380V rated) and is equipped with automatic alarm mechanisms, making it fully suitable for use in industrial pharmaceutical production facilities where flammable solvents are handled.
    Q How does the system ensure process monitoring and traceability?
    All key vessels feature sight-glass designs that allow real-time visual monitoring of pressure, temperature, and stirring status. Combined with metering pump-controlled quantitative solvent transfer and up to 9 solvent stations, the system ensures comprehensive process controllability and full traceability throughout the synthesis workflow.