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China Suppliers Factory: PepAxis™-Nova5 Microwave Peptide Synthesizer for Efficient Solid-Phase Synthesis
Channels1 / 12
Reactor Volume30 / 120 mL
Amino Acid Positions28
Synthesis Scale0.1–1.5 mmol
Dimensions (W×D×H)82 cm × 82 cm × 90 cm
PepAxis-Nova 5 (formerly 386 MW) is a fully automated microwave peptide synthesizer based on microwave-assisted solid-phase peptide synthesis (MW-SPPS) technology. By precisely directing microwave energy into the reaction system, it achieves highly efficient acceleration and optimization of peptide synthesis.
Compared with conventional water bath or hot air heating methods, this system delivers superior performance across every stage of the synthesis workflow.
⚡ Key Advantages Over Conventional Methods
- Rapid temperature ramping
- Uniform thermal field distribution
- Precise temperature control
- Significantly reduced energy consumption
>50%
Overall synthesis cycle shortened
1/30–1/10
Reaction time vs. conventional coupling & deprotection
100%
Fully automated control & data recording
PepAxis-Nova 5 is suitable for peptide drug R&D, biochemical research, and related material preparation fields, providing a reliable tool for efficient, energy-saving, and green synthesis of difficult sequences.
📋 Basic Parameters
| Type | Channels | Reactor (mL) | Amino Acid Sites | Activator Sites | Solvent Sites | Sizes (cm) |
|---|---|---|---|---|---|---|
| 386 MW | 1 or 12 | 30 / 120 | 28 | 4 | 4–7 | 77.5 × 55 × 84 |
⚙️ Technical Specifications
Temperature Control
Microwave heating, probe-based temperature control
Synthesis Mode
Sequential synthesis
Amino Acid Positions
28
Amino Acid Bottle Volume
125 mL
Activation Reagent Positions
4 positions, 125 / 250 mL bottles
Other Solvent Positions
4–6 positions, 0.5 L, 1 L, 2 L, 5 L, 10 L reservoirs
Precision Liquid Delivery
Quantitative aspiration, accuracy 0.1 mL
Mixing Mode
Nitrogen bubbling
Weight
75 kg
Power Supply
110 / 220 V, 50 / 60 Hz
❓ Frequently Asked Questions
Q
What is the main advantage of the PepAxis-Nova 5 over conventional peptide synthesizers?
The PepAxis-Nova 5 uses microwave-assisted solid-phase peptide synthesis (MW-SPPS), which enables rapid and uniform heating of the reaction system. Compared to traditional water bath or hot air methods, it offers faster temperature ramping, more precise temperature control, and can shorten the overall synthesis cycle by more than 50%, while significantly reducing energy consumption.
Q
How much faster are coupling and deprotection steps compared to conventional methods?
For critical steps such as amino acid coupling and deprotection, the PepAxis-Nova 5 can reduce reaction times to just 1/30–1/10 of those required by conventional synthesis methods, dramatically improving overall throughput and synthesis efficiency.
Q
What synthesis scales does the PepAxis-Nova 5 support?
The system supports synthesis scales ranging from 0.1 to 1.5 mmol, making it suitable for small-scale R&D work as well as more demanding research applications. It offers reactor volumes of 30 mL and 120 mL to accommodate different scale requirements.
Q
How many amino acid positions does the system accommodate, and what bottle sizes are supported?
The PepAxis-Nova 5 features 28 amino acid positions, each supporting 125 mL bottles. It also includes 4 activation reagent positions (125 mL or 250 mL bottles) and 4–6 additional solvent positions with reservoir sizes ranging from 0.5 L up to 10 L.
Q
Is the PepAxis-Nova 5 suitable for synthesizing difficult peptide sequences?
Yes. The system is specifically designed to handle difficult sequences that are challenging for conventional synthesizers. The precise microwave energy delivery ensures uniform heating and efficient coupling even for sterically hindered or aggregation-prone sequences, making it an ideal tool for green and efficient synthesis in peptide drug R&D and biochemical research.
Q
What are the power supply requirements and is the system compatible with different regional standards?
The PepAxis-Nova 5 supports both 110 V and 220 V power supplies at 50 or 60 Hz, making it compatible with electrical standards used in North America, Europe, Asia, and most other regions worldwide. No special power conversion equipment is typically required.



Advanced Microwave-assisted Solid-Phase Peptide Synthesis for faster results
Reduce coupling and deprotection time by 1/30–1/10 compared to traditional methods
Experience improved synthesis speed and efficiency with our state-of-the-art technology, made in China by reliable suppliers and factories