🧬 R&D Microwave Peptide Synthesizer
PepAxis-Nova 5 (formerly 386 MW) is a fully automated microwave peptide synthesizer based on microwave-assisted solid-phase peptide synthesis (MW-SPPS) technology. By precisely directing microwave energy into the reaction system, it achieves highly efficient acceleration and optimization of peptide synthesis.
Compared with conventional water bath or hot air heating methods, this system provides significant advantages across multiple dimensions:
Compared with conventional water bath or hot air heating methods, PepAxis-Nova 5 delivers outstanding performance improvements:
- Rapid temperature ramping
- Uniform thermal field distribution
- Precise temperature control
- Significantly reduced energy consumption
The overall synthesis cycle can be shortened by more than 50%. For critical steps such as amino acid coupling and deprotection, reaction times can be reduced to 1/30–1/10 of conventional methods, greatly improving synthesis efficiency.
The system is equipped with a fully automated control module, supporting precise parameter settings and comprehensive data recording, ensuring stable operation and good reproducibility.
PepAxis-Nova 5 is suitable for peptide drug R&D, biochemical research, and related material preparation fields, providing a reliable tool for efficient, energy-saving, and green synthesis of difficult sequences.
📋 Basic Parameters
| Type |
Channels |
Reactor (mL) |
Amino Acid Sites |
Activator Sites |
Solvent Sites |
Sizes (cm) |
| 386 MW |
1 or 12 |
30 / 120 |
28 |
4 |
4~7 |
77.5 × 55 × 84 |
⚙️ Technical Specifications
Temperature Control
Microwave heating, probe-based temperature control
Synthesis Mode
Sequential synthesis
Amino Acid Positions
28
Amino Acid Bottle Volume
125 mL
Activation Reagent Positions
4 positions, 125 / 250 mL bottles
Other Solvent Positions
4–6 positions, 0.5 L, 1 L, 2 L, 5 L, 10 L reservoirs
Precision Liquid Delivery
Quantitative aspiration, accuracy 0.1 mL
Mixing Mode
Nitrogen bubbling
Weight
75 kg
Power Supply
110/220 V, 50/60 Hz
❓ Frequently Asked Questions
Q
What is the key advantage of microwave-assisted synthesis over conventional heating methods?
Microwave-assisted synthesis provides rapid temperature ramping, uniform thermal field distribution, and precise temperature control. Compared to conventional water bath or hot air heating, the PepAxis-Nova 5 can shorten the overall synthesis cycle by more than 50%, while significantly reducing energy consumption.
Q
How much faster are coupling and deprotection steps with PepAxis-Nova 5?
For critical steps such as amino acid coupling and deprotection, the PepAxis-Nova 5 can reduce reaction times to 1/30–1/10 of those required by conventional synthesis methods, dramatically improving overall throughput and synthesis efficiency.
Q
What synthesis scale does the PepAxis-Nova 5 support?
The PepAxis-Nova 5 supports a synthesis scale ranging from 0.1 to 1.5 mmol, with reactor volumes of 30 mL or 120 mL, making it well-suited for R&D-scale peptide synthesis across a wide range of applications.
Q
Is the PepAxis-Nova 5 suitable for synthesizing difficult peptide sequences?
Yes. The system is specifically designed to handle difficult sequences. Its precise microwave energy delivery, probe-based temperature control, and nitrogen bubbling mixing mode enable efficient coupling even for challenging amino acid combinations, making it an ideal tool for green and efficient synthesis.
Q
What fields is the PepAxis-Nova 5 applicable to?
The PepAxis-Nova 5 is suitable for peptide drug R&D, biochemical research, and related material preparation fields. Its fully automated control module, comprehensive data recording, and stable reproducibility make it a reliable platform for laboratory and research-scale peptide synthesis.
Q
What are the power supply requirements and weight of the system?
The PepAxis-Nova 5 supports both 110 V and 220 V power supplies at 50/60 Hz frequency, making it compatible with laboratory environments worldwide. The system weighs approximately 75 kg and has dimensions of 77.5 × 55 × 84 cm.