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Industrial-Grade PepAxis™ Sirius Peptide Synthesizer - Reliable China Suppliers & Factory for Advanced Research Solutions
Product Profile
PepAxis™-Sirius (formerly 686) is a high-reliability industrial-grade customized peptide synthesis system designed for large-scale industrial production. The system adopts a modular customized design, with reactor volumes ranging from 30 to 2000 L and synthesis scales of 0.3 mol and above, meeting the requirements of continuous and large-batch production.
The system is equipped with a double-jacketed temperature-controlled reactor, an amino acid activation tank, and a piperidine buffer tank, all featuring sight-glass designs for real-time monitoring of pressure, temperature, and stirring status, ensuring full-process controllability and traceability. It supports multi-solvent position management and precise quantitative transfer via metering pumps.
Combined with mechanical agitation and a wide temperature control range (–20 to 50 °C), the system effectively ensures process stability and reproducibility. The system is certified for explosion protection and equipped with automatic alarm mechanisms, making it suitable for industrial-scale peptide drug production, process scale-up, and customized synthesis applications, providing customers with a safe, efficient, and scalable synthesis solution.
The system is equipped with a double-jacketed temperature-controlled reactor, an amino acid activation tank, and a piperidine buffer tank, all featuring sight-glass designs for real-time monitoring of pressure, temperature, and stirring status, ensuring full-process controllability and traceability. It supports multi-solvent position management and precise quantitative transfer via metering pumps.
Combined with mechanical agitation and a wide temperature control range (–20 to 50 °C), the system effectively ensures process stability and reproducibility. The system is certified for explosion protection and equipped with automatic alarm mechanisms, making it suitable for industrial-scale peptide drug production, process scale-up, and customized synthesis applications, providing customers with a safe, efficient, and scalable synthesis solution.
Reactor: 30–2000 L
Scale: ≥ 0.3 mol
Explosion-Proof Certified
Temp: –20 to 50 °C
Modular Design
Basic Parameters
| Model | Channels | Reactor (L) | Amino Acid Tank | Deprotection Tank | Synthesis Scale (mol) |
| PepAxis-Sirius | 1 | 30~2000 | 1 | 1 | ≥ 0.3 |
Technical Parameters
Frequently Asked Questions
Q
What reactor volume range does the PepAxis™-Sirius system support?
A
The PepAxis™-Sirius system supports reactor volumes ranging from 30 L to 2000 L, making it suitable for both pilot-scale and full industrial-scale peptide synthesis operations.
Q
What is the minimum synthesis scale supported by the PepAxis™-Sirius system?
A
The system supports synthesis scales of 0.3 mol and above, enabling continuous and large-batch production to meet industrial pharmaceutical manufacturing demands.
Q
What materials are used for the reactor and key tanks in the PepAxis™-Sirius system?
A
The reaction vessel, amino acid activation tank, and deprotection buffer tank are all constructed from 304 stainless steel with 316L stainless steel lining, ensuring excellent corrosion resistance and compatibility with pharmaceutical-grade solvents and reagents.
Q
What temperature control range does the PepAxis™-Sirius system offer?
A
The system provides a wide temperature control range of –20 °C to 50 °C using water or ethylene glycol as the temperature control medium, ensuring process stability and reproducibility across a broad range of synthesis conditions.
Q
Is the PepAxis™-Sirius system certified for use in explosion-risk environments?
A
Yes. The PepAxis™-Sirius system is certified for explosion protection and is equipped with automatic alarm mechanisms, making it fully compliant for use in industrial environments where flammable solvents are handled.
Q
How does the PepAxis™-Sirius system ensure process monitoring and traceability?
A
The system features sight-glass designs on the reactor, amino acid activation tank, and piperidine buffer tank, allowing real-time monitoring of pressure, temperature, and stirring status. Combined with precise quantitative transfer via metering pumps and up to 9 solvent stations, the system ensures full-process controllability and traceability.









Discover our large-volume dual-jacket temperature-controlled reactors, designed with viewports for enhanced observation. Our reactors are manufactured in China and are perfect for suppliers seeking reliable and high-quality equipment from a trusted factory.
Experience real-time monitoring and alarms that ensure precise control over pressure, solvent temperature, and stirring speed. This cutting-edge technology makes our reactors a top choice for suppliers and factories in need of advanced solutions.
Utilize quantitative solvent transfer with our efficient metering pumps, tailored for smooth operations. Partner with our reliable factory in China to enhance your production capabilities and meet your sourcing needs.