Atlas 2 (formerly 286 Pro) adopts a modular channel design. The 24 amino acid positions are allocated by group, divided into 4 positions per group. Each channel is equipped with an independent reactor, enabling multi-sequence parallel synthesis. The system adopts an "on-demand feeding, complete transfer" raw material management approach. Users weigh the required amino acids for each synthesis batch, and the instrument automatically performs one-time full transfer into the reactor. This effectively avoids reagent waste and is particularly suitable for mid-scale R&D applications involving expensive amino acids (e.g., 1–5 g impurity profile studies). Through a simplified and intelligent design, the instrument reduces operational complexity and is an ideal platform for peptide synthesis teaching, method standardization, and process optimization research.
🌡️ Temperature Control Method
Water bath / Electromagnetic induction
🧬 Amino Acid Positions
24, single aspiration
⚗️ Activation Reagent Positions
4, quantitative aspiration, accuracy 0.1 mL
🧴 Solvent / Reagent Positions
4–6
🪣 Solvent Reservoirs
0.5 L, 1 L, 2 L, 5 L, 10 L
🔄 Mixing Mode
Vortex agitation / Nitrogen bubbling
🔌 Power Supply
110 / 220 V, 50 / 60 Hz
❓ Frequently Asked Questions
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What is the Atlas 2 Peptide Synthesizer and who is it designed for?
The Atlas 2 (formerly 286 Pro) is a mid-scale automated peptide synthesizer featuring a modular channel design. It is designed for researchers, educators, and process development teams who require multi-sequence parallel synthesis, particularly for R&D applications involving expensive amino acids, teaching, and method standardization.
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How many channels and what reactor volumes does the Atlas 2 support?
The Atlas 2 supports 3 or 6 channels. Reactor volumes available include 25/50 mL for smaller-scale work and 100/200/500 mL for mid-scale applications, covering a synthesis scale of 0.1–3 mmol.
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How does the "on-demand feeding, complete transfer" raw material management work?
Users weigh the exact amount of amino acids needed for each synthesis batch. The instrument then automatically performs a one-time full transfer of these materials into the reactor. This approach eliminates reagent waste and is especially cost-effective when working with expensive amino acids in impurity profile studies (e.g., 1–5 g scale).
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What mixing modes are available on the Atlas 2?
The Atlas 2 supports two mixing modes: vortex agitation and nitrogen bubbling. These options ensure efficient reagent mixing and resin suspension throughout the synthesis process, which is critical for high coupling efficiency.
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What temperature control methods does the Atlas 2 offer?
The Atlas 2 provides two temperature control methods: water bath and electromagnetic induction. This flexibility allows users to optimize reaction conditions for different peptide sequences and coupling chemistries, including challenging sequences that benefit from elevated temperatures.
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What are the power and installation requirements for the Atlas 2?
The Atlas 2 is compatible with both 110 V and 220 V power supplies at 50/60 Hz, making it suitable for laboratories worldwide. The instrument weighs 87 kg and has dimensions of 90 cm × 62 cm × 82 cm (W × D × H), requiring adequate bench or floor space for installation.
