Dual-Channel Peptide Synthesizer
Channels: 2
Reactor Volume: 0.5 – 2 L
Amino Acid Positions: 10
Synthesis Scale: 2 – 25 mmol
Dimensions (W×D×H): 108 cm × 62 cm × 90.5 cm
Atlas 4 (formerly 286 Max) is a dual-channel synthesis system specifically designed for pilot-scale applications. It is capable of simultaneously synthesizing two different peptide sequences, effectively improving R&D efficiency. The system supports both synchronous activation and preactivation modes, enabling flexible adaptation to various synthesis process requirements. It adopts quantitative weighing and full-transfer technology combined with a 1 mL precision liquid dosing system. While ensuring efficient reaction control, it significantly reduces reagent waste, making it a reliable choice for pilot process development and small-to-medium scale synthesis.
Temperature Control Method
Water bath / Electromagnetic induction
Amino Acid Bottle Volume
250 mL
Solvent Reservoirs
0.5 L, 1 L, 2 L, 5 L, 10 L
Mixing Mode
180° vertical inversion + Nitrogen bubbling
Power Supply
110 / 220 V, 50 / 60 Hz
Q
What does "dual-channel" mean on the Atlas 4 peptide synthesizer?
Dual-channel means the Atlas 4 can run two independent synthesis reactions simultaneously. Each channel operates with its own reactor, allowing researchers to synthesize two entirely different peptide sequences in a single instrument run, significantly improving throughput and R&D efficiency.
Q
What synthesis scales does the Atlas 4 support?
The Atlas 4 supports synthesis scales ranging from 2 mmol to 25 mmol, with reactor volumes of 0.5 L, 1 L, and 2 L. This makes it well suited for pilot process development as well as small-to-medium scale production runs.
Q
What activation modes does the system support?
The Atlas 4 supports both synchronous activation and preactivation modes. This flexibility allows the system to adapt to a wide range of synthesis protocols and process requirements without hardware modification.
Q
How does the system minimize reagent waste?
The Atlas 4 employs quantitative weighing and full-transfer technology combined with a 1 mL precision liquid dosing system. This approach ensures that only the exact required amount of reagent is dispensed per cycle, substantially reducing unnecessary waste during synthesis.
Q
What mixing method is used in the reactor?
The reactor uses a combination of 180° vertical inversion mixing and nitrogen bubbling. This dual mixing approach ensures thorough and uniform contact between the resin and reagents, contributing to high coupling efficiency and consistent peptide quality.
Q
What are the power supply and installation requirements for the Atlas 4?
The Atlas 4 is compatible with both 110 V and 220 V power supplies at 50/60 Hz, making it suitable for laboratories worldwide. The instrument weighs 87 kg and has dimensions of 108 cm (W) × 62 cm (D) × 90.5 cm (H), requiring adequate bench space and load-bearing capacity for installation.