Peptide Fundamentals

Peptides, the "small molecules of life" composed of amino acid chains, have emerged as a critical breakthrough in addressing intractable medical challenges—including metabolic diseases, cancer, and drug-resistant infections—thanks to their unique...

The synthesis processes of polypeptide active pharmaceutical ingredients (APIs) are mainly divided into three categories: Solid-Phase Peptide Synthesis (SPPS), Liquid-Phase Peptide Synthesis (LPPS), and Fragment Condensation. Among them, SPPS has become the ...

Quality research on peptide active pharmaceutical ingredients (APIs) shall follow the principles of comprehensive characterization, precise control, and full-process traceability. Its core contents include impurity control, structural elucidation, stability ...

Atopic dermatitis (AD) is a highly prevalent chronic inflammatory skin disease globally, affecting 15%–30% of children and 2%–10% of adults. In the US alone, associated treatment costs exceed $5 billion annually. AD also significantly increases t...

In the field of efficacy skincare, oxidation and glycation are two fundamental drivers of skin aging. Oxidative damage disrupts cellular structures and collagen fibers, while glycation cross-links collagen, causing it to lose elasticity and leading to dull, ...

Cancer remains one of the leading causes of death worldwide, projected to claim 10 million lives by 2030. Current standard therapies, predominantly chemotherapy, lack tumor specificity and often cause severe off-target toxicities, limiting clinical efficacy ...

In the first three parts of this series, we analyzed representative peptides: palmitoyl pentapeptide-4 for collagen remodeling, acetyl hexapeptide-8 for neuromodulation, and copper tripeptide for repair and fortification. This installment focuses on the depi...

Foot-and-mouth disease (FMD) synthetic peptide vaccine is a new type of veterinary vaccine developed based on peptide technology, primarily used to prevent and control foot-and-mouth disease virus (FMDV) infection. FMDV is a highly contagious virus that main...