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Pilot Peptide Synthesizer PepAxis™-Atlas 6: Leading Suppliers and Factory in China for Automated Synthesis
Pilot-Scale Single-Channel Peptide Synthesizer
PepAxis-Atlas 6 Ⅰ
Number of Channels: 1
Reactor Volume: 0.5–2 L
Amino Acid Positions: 6
Synthesis Scale: 2–25 mmol
Dimensions (W × D × H): 70 cm × 60 cm × 75 cm
PepAxis-Atlas 6 Ⅱ
Number of Channels: 1
Reactor Volume: 1 / 2 / 5 L
Amino Acid Positions: 6
Synthesis Scale: 4–60 mmol
Dimensions (W × D × H): 85 cm × 85 cm × 90 cm
Atlas 6 (formerly 486 Pro) is a flexible single-channel system for pilot-scale synthesis, adaptable to different synthesis strategies. Users can freely replace reactor specifications according to requirements, enabling synthesis scales from 2–25 mmol (or up to 60 mmol depending on configuration). The instrument emphasizes operational autonomy and process scalability, providing a stable and efficient synthesis platform for process optimization and pilot-scale scale-up.
📋 Basic Parameters
| Type | Channels | Reactor (L) | Amino Acid Sites | Solvent Sites | Sizes (cm) |
|---|---|---|---|---|---|
| Atlas 6 | 1 | 0.5 / 1 / 2 | 6 | 5 | 70 × 60 × 75 |
| 1 / 2 / 5 | 6 | 5 | 85 × 85 × 90 |
⚙️ Technical Specifications
Temperature Control Method
Water bath heating
Amino Acid Bottles
50–200 mL
Solvent Positions
5
Solvent Reservoirs
20 L, 50 L
Mixing Mode
180° vertical inversion mechanical stirring
Power Supply
110 / 220 V, 50 / 60 Hz
Weight
87 kg
❓ Frequently Asked Questions
Q
What is the difference between PepAxis-Atlas 6 Ⅰ and Atlas 6 Ⅱ?
The primary difference lies in reactor volume and synthesis scale. Atlas 6 Ⅰ supports reactor volumes of 0.5–2 L with a synthesis scale of 2–25 mmol, while Atlas 6 Ⅱ supports larger reactor volumes of 1, 2, or 5 L and a synthesis scale of 4–60 mmol, making it more suitable for larger pilot-scale production needs.
Q
Can users change the reactor size on the Atlas 6 synthesizer?
Yes. The Atlas 6 is designed with operational flexibility in mind. Users can freely replace reactor specifications according to their synthesis requirements, allowing seamless adaptation between different scales without the need to replace the entire instrument.
Q
What mixing technology does the Atlas 6 use during synthesis?
The Atlas 6 employs 180° vertical inversion mechanical stirring as its mixing mode. This method ensures thorough and uniform mixing of reagents within the reactor, which is critical for consistent coupling efficiency and high-quality peptide synthesis at pilot scale.
Q
How many amino acid positions and solvent positions does the Atlas 6 support?
Both Atlas 6 Ⅰ and Atlas 6 Ⅱ support 6 amino acid positions and 5 solvent positions. Amino acid bottles range from 50 to 200 mL, and solvent reservoirs are available in 20 L and 50 L capacities to accommodate various synthesis workflows.
Q
What power supply specifications are required for the Atlas 6?
The Atlas 6 synthesizer is compatible with both 110 V and 220 V power supplies at 50 or 60 Hz, making it suitable for use in laboratories and facilities across different regions worldwide without requiring special power adaptations.
Q
Is the Atlas 6 suitable for process optimization and scale-up applications?
Yes. The Atlas 6 is specifically designed to support process optimization and pilot-scale scale-up. Its adaptable reactor configurations, stable water bath temperature control, and scalable synthesis range (from 2 mmol up to 60 mmol) make it an ideal platform for transitioning peptide synthesis from research-scale to production-ready processes.