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PSI486 Pilot Peptide Synthesizer

Pilot

PSI486 Pilot Peptide Synthesizer

PSI486 single-channel pilot-type fully automatic peptide synthesis instrument is a standing solid-phase peptide synthesis instrument for pilot-scale production of peptides. 

    Product Profile

    PSI486 single-channel pilot-type fully automatic peptide synthesizer is a standing solid-phase peptide synthesis instrument for pilot-scale production of peptides. Fully automated greatly saves labour cost, only need to set the order of amino acid addition, time duration, etc. in the software, and then the synthesis can be started automatically according to the program. Nitrogen/solvent is alternated periodically to clean the pipeline automatically.

    PSI486 Pilot Peptide Synthesizer is a specialized instrument designed for scaling up peptide synthesis processes from research and development (R&D) to larger, pilot-scale production. This type of synthesizer bridges the gap between small-scale laboratory synthesis and full-scale industrial production, making it ideal for producing peptides in quantities sufficient for early-stage clinical trials, process optimization, and pilot studies.

    Basic Parameters

    Model

     Channels

    Reactor/L

    Amino Acid Sites

    Solvent Sites

    Width×Depth×Height

    PSI-486

    1

    0.5 / 1 / 2

    8

    or 7

    70cm×60cm×75cm

    Specifications

    After the peptide chain is developed and screened in the laboratory, the second step is "small test", i.e. to amplify according to the laboratory results; the third step is "pilot test", i.e. to continue to amplify according to the results of the small test, and the target peptide chain can be mass-produced basically after the success of the pilot test.The PSI486 single-channel pilot-type fully automated peptide synthesis instrument was specially developed for the needs of the pilot test. 
    PSI486 single-channel pilot-type automatic peptide synthesis instrument adopts single-channel, single reactor synthesis scale is 2.5-20mmol; 6 amino acid tanks are convenient for users to customise a variety of amino acids, coupling agents, side chain groups, etc.; 7 solvent tanks can be placed in different commonly used solvents for washing, it is the standing solid-phase peptide synthesizer for the production of peptides on a pilot scale.
    The peptide synthesis instrument of American Peptide Technology Company adopts the mixing mode of "fixed reactor, stirring paddle pushing the solid-phase resin to collide with the reactants"; when the stirring paddle is activated, the resin is grinded and squeezed, and part of the resin is deformed and broken, which reduces the coupling rate; and the broken resin seeps into the gap of the sieve plate, which influences the speed of liquid discharging. In order to avoid resin damage, in 1995, JOHN YE successfully tested the mixing mode without stirring paddles, in which the solid-phase resin collides with the reactants by turning the reactor up and down, and the coupling efficiency increased to more than 99.5%.

    ●Scale: 2~25mmol
    ●Reactor: 0.5 / 1 / 2L 
    ●Amino acid sites: 8
    ●Amino acid tank: 250ml
    ●Solvent sites:5 or 7
    ●Solvent tank: 10L×3, 20L×2
    ●Solvent flow rate:1~2ml/sec
    ●Thermostat: water, oil or other media   
    ●Mixing systems: 180 degrees, “up and down” mixing
    ●Stirring speed: 0 to 30 rpm
    ●Machine material: 304 stainless steel
    ●Power:110/220 Volts.50/60 Hz
    ●Dimension:70cm×60cm×75cm
    ●Weight: 78kg

    After-sales Service

    Installation and commissioning: Provide professional technicians to install and commission the equipment to ensure that the equipment can operate correctly.
    Training: Provide operation, maintenance, maintenance training to help customers fully understand and master the use of equipment.
    Maintenance: Provide regular or on-demand equipment maintenance, maintenance services to ensure that equipment performance continues to be stable.
    Fault repair: In the event of equipment failure, to provide rapid maintenance services.
    Spare parts supply: Provide original or certified spare parts to ensure the quality and stability of replacement parts.
    Remote Support: Remotely assist customers to solve operation problems or simple faults through telephone, network and other means.
    On-site support: If the problem can not be solved remotely, send technicians to the site to provide support.
    Customer Support Hotline: Set up a customer support hotline to answer customer questions and provide technical support at any time.
    Satisfaction Survey: Conduct regular satisfaction surveys to collect customer feedback to improve the quality of after-sales service.